Thursday, January 31, 2013

Brooks Palmer: Clutter Busting a Relationship That Doesn't Serve You

I was talking with someone who said that she felt it's hard as a woman to let go of a relationship that no longer serves her. She felt she was raised to think that a woman's role was to be a nurturer and put other people's needs first. She said she has some friendships where the people were constantly taking from her and giving nothing back. But she just couldn't seem to say no to them.

I said that it's hard to take one for the team. It takes a toll to put ourselves in harm's way. We can reason with ourselves that it's okay to be hurt. But I encouraged her to look deeper at the effects it produces on her both physically and psychologically.

She said the pain she endured from these relationships made her feel hallow, like her insides had been removed and she's just a machine. She said it made it hard for her to find joy in other parts of her life.

I said that's a huge toll to pay for pseudo companionship. A relationship supports us when it makes us feel connected. Our hearts relish that feeling of unity. But when we suffer to maintain a relationship, we lose that beautiful feeling of connection. It made sense she felt like a machine.

I said that I recently had a difficult relationship experience. The other person would occasionally become harsh and critical of my life. I let them know that I didn't like their behavior. They apologized and stopped being that way for a while. But then they went back to it. So I mentioned again that it was making me uncomfortable. They stopped. And then about a week later they left me a mean-spirited phone message. So I contacted that person and said that I no longer wanted to be friends with them. It felt good to take care of myself.

She said it was sobering to look matter-of-factually at her experiences. She felt deep down that there was a quiet and gentle part of herself that needed the nurturing she was giving to others who weren't kind to her.

Please write and tell me your experiences clearing relationships that are clutter; it helps inspire people when you share.


Brooks Palmer is the author of Clutter Busting: Letting Go of What's Holding You Back (New World Library, 2009) and Clutter Busting Your Life: Clearing Physical and Emotional Clutter to Reconnect With Yourself and Others (New World Library, 2012). To schedule an over-the-phone clutter busting session, go to http://www.clutterbusting.com.

For more by Brooks Palmer, click here.

For more on emotional wellness, click here.

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Source: http://www.huffingtonpost.com/brooks-palmer/relationship-friendship-advice_b_2568338.html

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What We're Reading - NYTimes.com - Diner's Journal - New York ...

The Daily Meal: Someone is selling a moldy Twinkie on eBay. Year-old. Unpackaged. A significant test of Twinkie shelf-life! ? Glenn Collins

Food Republic: Microwave popcorn has apparently been with us so long that some people (sadly) don?t know of any other kind. How else to explain these step-by-step instructions for old-fashioned stovetop popping? ? Patrick Farrell

The Washington Post: Some chefs are trying to turn the homely Chesapeake Bay snakehead into a swan of a main course. ? Maria Newman

Poetry Foundation: ?The drink storms through these men,? Robin Robertson writes in a great poem about fishermen. ? Jeff Gordinier

Bloomberg Businessweek: The sad, cautionary tale of the 81 percent sales decline of the diet drink Slim-Fast over the last decade ? while the booming replacement-meal category has spiked 27 percent over the last four years. ? Glenn Collins

Esquire: As caffeine-and-alcohol combinations go, trust us, you can do much better than that tacky mash-up of Red Bull and vodka. Consider this: rye paired with sweet vermouth that?s been infused with Earl Grey tea. ? Jeff Gordinier

The Washington Post: Students at the University of Maryland who collect leftover dorm food to donate to Washington shelters have spread their work to other campuses. ? Maria Newman

Wild Fermentation: A bright red paste you can make by fermenting tomatoes, provided you don?t mind a little ?spidery-looking mold.? ? Jeff Gordinier

The Wall Street Journal: You are not alone, you Wi-Fi warriors at Starbucks. For many in rural communities, after the library and the computer lab close for the night, there is only one place to turn for Internet access: McDonald?s, which has 12,000 wireless-equipped locations in the United States. (Subscription required.) ? Glenn Collins

Boston Magazine: An exhaustive guide to finding the best Asian food in Boston. ? Jeff Gordinier

The New York Times: Mark Bittman makes the case for turning lawns into gardens. ? Maria Newman

LA Weekly: A mochi shop in downtown Los Angeles is, remarkably, 110 years old. ? Jeff Gordinier

Source: http://dinersjournal.blogs.nytimes.com/2013/01/30/what-were-reading-618/

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Late Lunch May Mean Less Weight Loss - Health News and Views ...

nutrition 40102 Late Lunch May Mean Less Weight Loss

By Amy Norton
HealthDay Reporter

TUESDAY, Jan. 29 (HealthDay News) ? People who like to eat lunch late in the afternoon may have more trouble shedding pounds than those who dine earlier, a new study suggests.

Researchers found that of 420 people in a weight-loss program, the late-lunch crowd lost about 25 percent less weight than those who usually lunched before 3 p.m.

The findings, reported Jan. 29 in the International Journal of Obesity, come with caveats. The researchers cannot be sure that a late lunch itself thwarts people?s diets. And the study participants were from Spain, where lunch is the biggest meal of the day.

It?s not clear if the findings would translate to a country like the United States, where most people eat a lighter lunch and save their main meal for dinner, said senior researcher Frank Scheer, an assistant professor of medicine at Harvard Medical School in Boston.

It is a common belief that it?s better to have your big meal earlier in the day. Scheer pointed to the popular advice to eat breakfast like a king and dinner like a pauper. But there hasn?t been much scientific evidence that the timing of your main meal matters in the battle of the bulge.

?This is the first large-scale, long-term study to show that it is an important factor in weight-loss success for overweight and obese individuals,? Scheer said.

It?s uncertain why a late lunch would be related to slower weight loss. One possibility, though, is that at least some late lunchers were going too long between meals, which might have effects on metabolism.

Some studies have suggested that evenly spaced meals ? eating every three to four hours ? are helpful in weight control, noted Connie Diekman, director of university nutrition at Washington University in St. Louis.

In this study, the late-lunch group was more likely to eat a light breakfast or skip breakfast altogether. Almost 7 percent of later lunchers did so, versus less than 3 percent of people who ate lunch earlier.

So the findings show a ?potential connection between going too long between meals and weight gain,? said Diekman, who was not involved in the study. ?But given the study design, more studies are needed to determine if there is a cause-and-effect connection.?

The problem is that people who hold off on lunch may differ from other dieters in many ways ? including ways that could hinder their weight loss.

Scheer?s team did account for some of those possibilities. They found that the early- and late-lunch groups ate a similar number of calories and burned a similar amount (based on their reported activity levels). The two groups also averaged about the same amount of sleep each night, which is important because sleep loss has been linked to a higher risk of obesity and less weight-loss success.

Still, that?s not enough to prove the late lunch caused the slower weight loss, Scheer and Diekman pointed out.

The findings are based on 420 overweight and obese Spanish adults who took part in a five-month weight-loss program. They were encouraged to follow a traditional Mediterranean diet, which includes plenty of fish, olive oil, vegetables and whole grains, but goes light on red meat and butter.

They got no advice, however, on the timing of their meals.

In the end, the half of the group that usually ate lunch after 3 p.m. lost an average of 17 pounds. That compared with 22 pounds in the early-lunch group.

As is typical in Spain, lunch was the biggest meal of the day. The dieters downed 40 percent of their daily calories at lunchtime, on average ? whether they ate early or late.

In contrast to the lunch findings, there was no evidence that the timing of people?s breakfast or dinner affected their weight loss. (Half of the group ate their dinner after 9:30 p.m.)

So in a culture where the biggest meal of the day is dinner, would it matter if you ate it at 9 p.m. or 6 p.m.? ?It?s hard to say, based on these data,? Scheer said. Further research is needed to answer that question, he added.

For now, the current findings are in line with animal research showing that meal timing seems to affect weight, Scheer said.

It may have to do with effects on the body?s circadian rhythms, which influence a range of functions, including the sleep-wake cycle and metabolism. There is a ?master clock? in the brain that coordinates those rhythms, but there are also ?peripheral clocks? in tissue and cells throughout the body, Scheer explained.

In animals, unusual feeding times seem to disrupt some of those peripheral clocks and throw them out of sync with the master clock. In theory, that clock ?decoupling? could affect weight control.

More research is still needed, though, to see whether the timing of a person?s main meal directly influences weight ? and how important that influence really is, Scheer said.

?We need to know if this has clinical relevance,? he said.

Diekman said the findings support the notion that meal timing matters, but she agreed that the ultimate importance to weight loss remains to be seen.

?As a registered dietitian, this study helps me feel comfortable with recommendations about the importance of meal spacing,? she said. ?But it does not give an answer to why or what impacts that might have on weight.?

More information

Learn more about weight-loss dieting from the U.S. National Institutes of Health.

HEALTHDAY Web XSmall Late Lunch May Mean Less Weight Loss

Source: http://news.health.com/2013/01/29/late-lunch-may-mean-less-weight-loss/

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Wednesday, January 30, 2013

Homeownership rate slips, rental vacancies up

WASHINGTON (Reuters) - The share of privately owned homes edged down in the fourth quarter and rental vacancies rose, government data showed on Tuesday, underscoring the challenges still confronting the housing market recovery.

The homeownership rate slipped to 65.4 percent from 65.5 percent in the third quarter, the Commerce Department said.

While the housing market recovery appears to be gaining traction, high unemployment and stringent lending standards are keeping many from owning a home.

The homeownership rate peaked at 69.2 percent in 2004 at the height of a housing market boom fueled by cheap credit.

In the fourth quarter, the home ownership rate was pulled down by a 1.4 percentage points decline in ownership among the 35-44 age group.

The residential rental vacancy rate ticked up to 8.7 percent from 8.6 percent in the third quarter. It peaked at 11.1 percent in the third quarter of 2009.

Owner-occupied housing units made up 56.6 percent of total housing units, while renter-occupied units made up 30.0 percent of the inventory in the fourth quarter of 2012.

Vacant units that were held off market comprised 5.5 percent of the total housing stock. The share of empty privately owned houses was steady at 1.9 percent.

(Reporting by Lucia Mutikani; Editing by Andrea Ricci)

Source: http://news.yahoo.com/homeownership-rate-slips-rental-vacancies-164338594--business.html

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After gun crime, weapon history takes time to find

(AP) ? In the fictional world of television police dramas, a few quick clicks on a computer lead investigators to the owner of a gun recovered at a bloody crime scene. Before the first commercial, the TV detectives are on the trail of the suspect.

Reality is a world away. There is no national database of guns. Not of who owns them, how many are sold annually or even how many exist.

Federal law bars the Bureau of Alcohol, Tobacco, Firearms and Explosives from keeping track of guns. The only time the government can track the history of a gun, including its first buyer and seller, is after it's used in a crime. And though President Barack Obama and numerous Democratic lawmakers have called for new limits on what kinds of guns should be available to the public and urged stronger background checks in gun sales, there is no effort afoot to change the way the government keeps track ? or doesn't ? of where the country's guns are.

And tracing a gun is a decidedly low-tech process.

"It's not CSI and it's not a sophisticated computer system," said Charles J. Houser, who runs the ATF's National Tracing Center in Martinsburg, W. Va.

To trace a gun, the search starts with police sending all the information they have about the gun ? including the manufacturer and model ? to an office worker in a low-slung brick building just off the Appalachian Trial in rural West Virginia, about 90 miles northwest of Washington.

ATF officials first call the manufacturer, who reveals which wholesaler the company used. That may lead to a call to a second distributor before investigators can pinpoint the retail gun dealer who first sold the weapon. Gun dealers are required to keep a copy of federal forms that detail who buys what gun and a log for guns sold. They are required to share that information with the ATF if a gun turns up at a crime scene and authorities want it traced. Often, gun shops fax the paperwork to the ATF.

That's where the paper trail ends.

In about 30 percent of cases, one or all of those folks have gone out of business and ATF tracers are left to sort through potentially thousands of out-of-business records forwarded to the ATF and stored at the office building that more closely resembles a remote call center than a law enforcement operation.

The records are stored as digital pictures that can only be searched one image at a time. Two shifts of contractors spend their days taking staples out of papers, sorting through thousands of pages and scanning or taking pictures of the records.

"Those records come in all different shapes and forms. We have to digitally image them, we literally take a picture of it," Houser said. "We have had rolls of toilet paper or paper towels ... because they (dealers) did not like the requirement to keep records."

The tracing center receives about a million out-of-business records every month and Houser runs the center's sorting and imaging operations from 6 a.m. to midnight, five days a week. The images are stored on old-school microfilm reels or as digital images. But there's no way to search the records, other than to scroll through one picture of a page at a time.

"We are ... prohibited from amassing the records of active dealers," Houser said. "It means that if a dealer is in business he maintains his records."

Last year the center traced about 344,000 guns for 6,000 different law enforcement agencies. Houser has a success rate of about 90 percent, so long as enough information is provided. And he boasts that every successful trace provides at least one lead in a criminal case.

"It's a factory for the production of investigative leads," Houser said of the tracing center.

A 1968 overhaul of federal gun laws required licensed dealers to keep paper records of who buys what guns and gave ATF the authority to track the history of a gun if was used in a crime. But in the intervening decades, the National Rifle Association and other gun rights groups lobbied Congress to limit the government's ability to do much with what little information is collected, including keeping track on computers.

"They (lawmakers) feel that the act of amassing those records would in essence go a step toward creating an artificial registration system," Houser said.

What the ATF can do is give trace information to the law enforcement agency that asked for it and in some cases uses the data to help point them in the direction of other crimes.

Houser said the "manually intensive process" can take about five days for a routine trace. In some cases, completing the trace can mean sifting by hand through paperwork that hasn't yet been scanned.

In more urgent situations, including the immediate aftermath of a mass shooting in Connecticut last year, ATF agents run a trace within about 24 hours. Oftentimes, that involves sending agents to the gun dealer that first sold the weapon to quickly find the paperwork listing its original buyer.

Despite having access to millions of records about gun purchases from dealers that have gone out of business, the ATF isn't allowed to create a database of what guns were sold to whom and when.

ATF does keep tabs on how many guns are manufactured and shipped out of the country every year, but only gun makers and dealers know for sure how many are sold. There are also strict limits on what the agency can do with the gun trace information. And that's just the way the gun lobby and Congress want it.

Various laws and spending bills have specifically barred the ATF from creating a national database of guns and gun owners. And due to the efforts of lawmakers, including former Rep. Todd Tiahrt of Kansas, ATF agents who trace the history of a gun can't share that information with anyone but the police agency that asked for it.

As it stands now, local law enforcement doesn't have access to regional data about gun traces. So if the police commissioner in New York City is trying to figure out where the guns are coming into the city from ? whether they're going to New Jersey first or upstate New York, for example ? that data is not available because of an amendment introduced by Tiahrt, said Mike Bouchard, a former ATF assistant director for Field Operations. ATF can tell police where most crime guns are traced from, by state. But it does not release information on gun shops or purchasers.

If police chiefs want that, they have to reach out to individual chiefs at other departments and ask.

"It's pretty ridiculous when we have an automated system that will do it for the chiefs," Bouchard said.

Tiahrt said he first proposed limiting access to trace data to make sure the information wasn't available under the U.S. Freedom of Information Act. It was an issue of keeping undercover police, informants and innocent gun buyers and sellers out of the public eye, Tiahrt said in a recent interview with The Associated Press.

Knowing who legally buys guns won't prevent gun violence, the former Republican congressman said.

"We're chasing these wisps of smoke that won't solve the problem," Tiahrt said. "Get to the root cause. Put out the fire. Deal with mental illness. Deal with situational awareness."

Houser said he would prefer the tracing center's operations to be expanded and a center built that would use some technologies to help more easily trace a gun. But until the law changes, his staff will continue removing staples, turning pages right-side-up and taking digital pictures of records.

"Our job is to enforce the laws that are passed to us," Houser said. "What they give us is what we are required to work with."

___

Associated Press reporter Eileen Sullivan contributed to this report.

___

Follow Alicia A. Caldwell on Twitter at www.twitter.com/acaldwellap

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-01-29-Tracing%20Guns/id-1b675fe7bbf34451a2c2d624d34038ca

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US consumers less optimistic after tax increase

WASHINGTON (AP) ? An increase in Social Security taxes is leaving Americans with less take-home pay ? and a more negative outlook for the U.S. economy.

The Conference Board said Tuesday that its index of consumer confidence plunged 8.1 points in January from December to 58.6. That's the lowest reading in 14 months and the third straight decline.

Congress and the White House reached a deal in January to keep income taxes from rising on most Americans. But the agreement did not extend a temporary cut in the Social Security taxes.

The tax increase will leave a household earning $50,000 a year with about $1,000 less to spend in 2013. A household with two high-paid workers will have up to $4,500 less.

The private research group said the tax hike was the key reason consumers felt less confident in January. The survey was conducted through Jan. 17, at which point most people began to realize their paychecks were lighter.

"It may take a while for confidence to rebound and consumers to recover from their initial paycheck shock," said Lynn Franco, the Conference Board's economist.

Consumers also said they felt less optimistic about their job prospects over the next six months.

Taxes are rising at a time when hiring is limited and wages are barely growing. The combination is expected to hurt consumer spending and slow economic growth.

"Perhaps more important than the shock to confidence, the hit to income is also likely to show up in a slower pace of consumer spending in the first half of this year," said Thomas Feltmate, an economist at TD Economics, in a note to clients.

The index has declined for three straight months since hitting a nearly five-year high of 73.1 in October 2012. It's still above the post-recession low of 40.9 reached in October 2011.

Consumers began to feel less optimistic at the end of the year when it appeared congressional Republicans and President Barack Obama were at an impasse over sharp spending cuts and tax increases.

Obama reached a deal with Republicans on Jan. 1 that kept most Americans from seeing higher income taxes. But they postponed decisions on spending cuts and raising the nation's debt limit until later in the year. And they allowed the Social Security tax cut to expire.

"All the negative news about the dysfunction in Washington surrounding the fiscal cliff negotiations contributed to the December plunge, and ongoing shenanigans concerning the debt ceiling and fiscal sanity in general continued to weigh in January," said Joshua Shapiro, chief U.S. economist at MFR Inc., in a note to clients.

Many economists predict economic growth slowed in the October-December quarter to an annual rate of around 1.2 percent. That would be much weaker that the 3.1 percent rate in the July-September quarter.

Most economists say the tax increase will hold back growth in the first quarter of 2013.

The decline in confidence comes as the economy is signaling improvement elsewhere.

A recovery in housing market is looking more sustainable and is expected to strength this year.

A separate report Tuesday showed home prices accelerated this fall, pushed higher by rising sales and a tighter supply of available homes. The Standard & Poor's/Case-Shiller 20-city home price index rose 5.5 percent in November compared with the same month a year ago. That's the largest year-over-year gain in six years.

The U.S. auto industry and financial sector are also picking up.

Auto sales reached a five-year high of 14.5 million in 2012. Analysts expect sales will climb even higher this year, to 15.5 million.

Stocks are near their all-time highs. The Standard and Poor's 500 has more than doubled from its low in 2009.

Still, the job market remains sluggish. Employers have added an average of about 150,000 jobs a month for the past two years. That's enough for a gradual decline in the unemployment rate, which remains high at 7.8 percent.

Source: http://news.yahoo.com/us-consumers-less-optimistic-tax-increase-210954179--finance.html

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US eyes drone base in Africa with al-Qaida in mind

FILE - In this Dec. 8, 2012, file photo, Malians demonstrate in favor of an international military intervention to regain control of the country's Islamist-controlled north, in Bamako, Mali. They carry signs that say 'That's enough, let the government work' right, and 'We Malians Demand Chapter 7,' center, referring to the chapter of the United Nations Charter which would be used to authorize international military intervention. The Pentagon is moving toward setting up a military base in northwest Africa from which to operate surveillance drones to collect intelligence on Islamic militants in the region, several U.S. defense officials said Tuesday, Jan. 29, 2013. The officials, speaking on condition of anonymity because the plan is still in the works, said the base in Niger would position the U.S. to provide more help to French troops fighting al-Qaida-backed militants in neighboring Mali. (AP Photo/Harouna Traore)

FILE - In this Dec. 8, 2012, file photo, Malians demonstrate in favor of an international military intervention to regain control of the country's Islamist-controlled north, in Bamako, Mali. They carry signs that say 'That's enough, let the government work' right, and 'We Malians Demand Chapter 7,' center, referring to the chapter of the United Nations Charter which would be used to authorize international military intervention. The Pentagon is moving toward setting up a military base in northwest Africa from which to operate surveillance drones to collect intelligence on Islamic militants in the region, several U.S. defense officials said Tuesday, Jan. 29, 2013. The officials, speaking on condition of anonymity because the plan is still in the works, said the base in Niger would position the U.S. to provide more help to French troops fighting al-Qaida-backed militants in neighboring Mali. (AP Photo/Harouna Traore)

In this photo taken on Monday, Jan. 28, 2013, provided by the French Army Communications Audiovisual office (ECPAD) and released Tuesday, Jan. 29, 2013, a French soldier walks near armored vehicles at the Timbuktu airport, north Mali. Backed by French helicopters and paratroopers, Malian soldiers entered the fabled city of Timbuktu on Monday after al-Qaida-linked militants who ruled the outpost by fear for nearly 10 months fled into the desert, setting fire to a library that held thousands of manuscripts dating to the Middle Ages. (AP Photo/French Army Communications Audiovisual office (ECPAD), Arnaud Roine)

In this picture taken on Monday, Jan. 28, 2013, provided by the French Army Communications Audiovisual office (ECPAD) and released Tuesday, Jan. 29, 2013, a French soldier, second from right, shakes hands with a resident of Timbuktu, north Mali. Backed by French helicopters and paratroopers, Malian soldiers entered the fabled city of Timbuktu on Monday after al-Qaida-linked militants who ruled the outpost by fear for nearly 10 months fled into the desert, setting fire to a library that held thousands of manuscripts dating to the Middle Ages.(AP Photo/French Army Communications Audiovisual office (ECPAD), Arnaud Roine)

WASHINGTON (AP) ? Plans to base unarmed American surveillance drones in the African nation of Niger highlight the Obama administration's growing concern about extremist influences in the volatile region. They also raise tough questions about how to contain al-Qaida and other militant groups without committing U.S. ground forces in yet another war.

In the short run, a drone base would enable the U.S. to give France more intelligence on the militants that French troops are fighting in neighboring Mali. Over time it could extend the reach not only of American intelligence gathering but also U.S. special operations missions to strengthen Niger's own security forces.

The U.S. and Niger in recent days signed a "status of forces agreement" spelling out legal protections and obligations of American forces that might operate in Niger in the future.

Pentagon spokesman George Little acknowledged the agreement, but declined Tuesday to discuss U.S. plans for a military presence in Niger.

"They expressed a willingness to engage more closely with us, and we are happy to engage with them," Little said, adding that the legal agreement was months in the making and saying it was unrelated to the recent fighting in Mali.

The U.S. has found some of its efforts to fight extremists hobbled by some African governments, whose own security forces are ill-equipped to launch an American-style hunt for the militants yet are reluctant to accept U.S. help because of fears the Americans will overstay their welcome and trample their sovereignty.

At France's request, the U.S. has flown 17 Air Force transport flights to move French troops and their equipment to Mali in recent days, Little said. U.S. aircraft also are conducting aerial refueling of French fighter jets based in Mali, he said, and those operations will continue.

Other U.S. officials said the Pentagon is planning a new drone base in northwestern Africa ? most likely in Niger ? but the plans are not yet complete. It would provide more extended U.S. aerial surveillance of militants in the region without risking the loss of air crews. The main U.S. drone base in Africa is in Djibouti in East Africa.

Niger has accepted the idea of hosting unarmed U.S. drones as well as conventional and special operations troops to advise and assist Niger's military on border security, but it has not endorsed armed U.S. Predator strikes or the launching of U.S. special operations raids from their territory, according to a senior U.S. military official briefed on the matter. The official spoke on condition of anonymity because the official was not authorized to speak publicly.

Africa is increasingly a focus of U.S. counterterrorism efforts, even as al-Qaida remains a threat in Pakistan, Yemen and elsewhere. The recent terrorist attack on a natural gas complex in Algeria, in which at least 37 hostages and 29 militants were killed, illustrated the threat posed by extremists who have asserted power propelled by long-simmering ethnic tensions in Mali and the revolution in Libya.

A number of al-Qaida-linked Islamic extremist groups operate in Mali and elsewhere in the Sahara, including a group known as Al-Qaida in the Islamic Maghreb, or AQIM, which originated in Algeria and is active in northern Mali. Earlier this month French forces intervened to stop the extremists' move toward Mali's capital, and Washington has grown more involved by providing a variety of military support to French troops.

In Addis Ababa on Tuesday, several African and Western nations pledged more than $450 million to fund an African-led military force to fight Islamist extremists in the Mali. And Britain announced it had offered to send up to 200 military officers to help train a West African force in Mali, including as many as 40 who could be sent as part of a European Union training mission of 500 personnel.

African nations including Ethiopia, Ivory Coast, Gambia and others lined up with developed countries including the United States, Japan, Germany and the United Kingdom to pledge money for the military effort. The U.S. share is to be $96 million, pending congressional approval.

As for al-Qaida-linked groups operating in Mali and elsewhere in northern Africa, the issue for the Obama administration is the degree to which they threaten U.S. security interests.

"AQIM poses a threat in the region, and I can't rule out the possibility that AQIM poses a threat to U.S. interests," Little said. "This is a group that has shown its ability to demonstrate brutality and to conduct attacks. And it is very important that we work with our partners in the region and our allies to thwart them."

Army Gen. Carter Ham, the commander of U.S. Africa Command, said last week that the worry is not just the intentions of AQIM but the ability of like-minded groups to leverage their capabilities by working together.

"We're starting to see the increasing collaboration, sharing of funding, sharing recruiting efforts, sharing of weapons and explosives and certainly a sharing of ideology that is expanding and connecting these various organizations," Ham said at Howard University. "And I think that's what poses at least the greatest immediate threat in the region."

The administration has ruled out sending U.S. ground forces to Mali. Its view is that military involvement, while necessary, is not a solution to the region's problems.

"We have said all along that there has to be more than a purely security solution to the problems in Mali, that the security track and the political track have to go hand-in-hand, that a key component of returning stability to Mali includes new elections and overturning the results of the coup firmly," State Department spokeswoman Victoria Nuland told reporters on Monday. She was referring to the coup last spring that prompted the U.S. to withdraw military trainers and cut off other forms of direct military assistance.

Some of the Malian troops that had received U.S. training wound up siding with the rebels in the north, and others who remained loyal to the government proved incapable of standing their ground against the militants.

Adm. Bill McRaven, commander of U.S. Special Operations Command, told a Washington conference on Tuesday that the key to future U.S. training operations like that is to ensure that the effort is long-lasting.

"We had an episodic presence in Mali," McRaven said, "and while I don't know if a persistent presence would have changed our relationship with the Malian forces -- whether they would have exponentially gotten better or not. "But in order to work with a host country, you really have to have that persistent presence."

___

Associated Press writers Writer Kimberly Dozier and Pauline Jelinek in Washington and Kirubel Tadesse in Ethiopia contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-01-29-US-Africa-Al-Qaida/id-4433f6797e0248979fe3ab0e121acfdf

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Tuesday, January 29, 2013

Solar Walk (for iPad)


While the Editors' Choice Star Walk 6 (for iPad) reveals the night sky, including constellations, star clusters, galaxies, nebulae, and planets, another Vito Technology app, Solar Walk (for iPad) ($2.99), focuses on our solar system. It lets you view and scale 3D representations of the Sun, planets, comets, and asteroids, view information on, and (in most cases) images of these objects, and view the solar system (or a planet and its moons) in motion. This impressive iPad app provides a good introduction to the solar system for younger students as well as newcomers to astronomy.

After the app's gorgeous opening screen, showing an artist's view of the inner solar system, the app zeroes in on Earth, showing satellites and their orbits around it, continents, vegetation, clouds, and seas, and the lights on our planet's night side when you rotate it (by sweeping your finger across the screen).

One fun feature of Solar Walk is the time slider along the right-hand edge, coupled with the digital clock at upper right. By setting the clock for minutes, hours, days, months, or years and engaging the slider, you can enable the Earth to rotate (and watch artificial satellites in motion, at least at the slower speeds). If you expand the view by pinching, it will show the Moon in motion around the Earth as well. You can either control the motion by hand, or set the slider in motion by sweeping your finger upwards or downwards and letting go.

Your Personal Transporter
At the screen's lower left is a Search button. It will transport you to other objects: the Sun; the planets (Pluto is included as such); dwarf planets and asteroids (Ceres, Makemake, Haumea, Sedna, Eris, and Eros); and comets (Halley's Comet, Hale-Bopp, Borrelly, and Ikeya-Zhang).

Clicking on the information ("i") icon for a world gives you general information about it, figures (data), some info on the world's internal structure, and a list of science missions to it.

By using the slider and clock, you can set these objects in motion as well, so you could watch, for example, the globe of Mars rotate (surface features are marked, and there's a 3D depiction of the Curiosity rover at Gale Crater); Jupiter's cloud belts rotating, and its four large moons in orbit; or the pear-shaped nucleus of Halley's Comet releasing clouds of gas and dust as it rotates. Expanding the Sun view shows you the planets in motion, although its scale is such that the inner planets vanish when you expand the view to encompass the outer worlds.

Also in Search are tabs marked Satellites, Geography, and Stars. With Satellites, you can zero in on specific Earth-orbiting artificial satellites, the Hubble Space Telescope and the International Space Station (ISS) the most notable of them. Clicking on a satellite name/icon will take you to a close-up view (a detailed 3D representation) of it in space. By rotating a satellite and using the time slider, you can make it seem like the satellite is orbiting the Earth, with the ground, ocean, or clouds passing beneath it. (This works better with the ISS than with smaller satellites.) As with planets and other objects, you can access an information page and image gallery.

We Lost New York
The Geography tab gives you a choice of four worlds: Moon, Mars, Earth, and Venus. Clicking on one gives you a list of features, both well known and obscure, in alphabetical order. Clicking on any of them takes you to the feature's location, where it's labeled on the planet's rotatable globe, as are other features. On the Earth map, most large cities are shown, although there are some notable omissions. For instance, in the United States, Los Angeles, San Francisco, Houston, Chicago, Jacksonville, and Washington D.C. are shown, but New York City, for one, seems to have vanished. Hamilton, Bermuda, Thorshavn, capital of the Faroe Islands, and Longyearbyen on Svalbard are shown, but more notable island cities like San Juan, Puerto Rico, Honolulu or, for that matter, Dublin, are missing.

The Stars tab takes you to selected stars. They're shown in their true colors, more or less; for instance, Sirius is bluish, while Barnard's Star is reddish. They're all depicted at the same size; although you can adjust their distance (and therefore, their apparent size) there's no scale, so you wouldn't know by looking at them Sirius is much larger than Barnard's Star, and Betelgeuse much larger than Sirius). They're all shown as single stars, whereas many are double (as is the case with Sirius) or triple (like Rigel Kentaurus, aka Alpha Centauri). The astronomical data you can call up for each star does indicate which are multiple stars, as well as their mass and radius compared with the Sun?if you know how to read it. And although most bright stars are shown, as well as many fainter ones, once again there are some notable omissions, like the brilliant stars Antares, Rigel, Spica, Deneb, and Canopus (the third brightest star in the sky).

At the top left is a Share button that lets you send a screenshot to email or Facebook, tweet it, save it to camera roll, print it, and rate or gift the app.

The Movies section presents educational animations of some (mostly) basic astronomical phenomena. They include Size Comparison [of worlds], Earth's Cycles, Solar Eclipse, The Moon Phases, Tidal Phenomena, Major Circles of Latitude, Zodiacal Constellations, and Cassini-Huygens. They're brief and basic, but do impart useful information to people new to astronomy.

Solar Walk also runs on an iPhone, with the same basic features and functionality. Though fine on an iPhone, the iPad's more generous screen only serves to enhance the experience.

Solar Walk is not quite as intuitive as Solar System, and its 3D graphics generally aren't as stunning. Both apps have gorgeous image galleries. There are some curious selections and omissions to Solar Walk's geography and star Search features. But the app has some good features, including introductory videos, searches, social media integration, and a more modest price.

More iPad App Reviews:

??? Solar System (for iPad)
??? Solar Walk (for iPad)
??? iHeartRadio (for iPad)
??? Temple Run 2 (for iPad)
??? 3D Brain (for iPad)
?? more

Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/GeF4TNeL3oU/0,2817,2414733,00.asp

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Why Civil War Hunley sub tanked

NORTH CHARLESTON, S.C. (AP) ? Scientists say a pole on the front of the Confederate submarine H.L. Hunley designed to plant explosives on enemy ships may hold a key clue to its sinking during the Civil War.

The experts are to release their findings Monday at a North Charleston lab where the hand-cranked sub is being preserved and studied. The Hunley was the first submarine in history to sink an enemy warship.

The pole, called a spar, was once placed at the front of the sub and used to plant a powder charge into the Union blockade ship Housatonic in 1864.The Housatonic sank, while the Hunley and its eight-man crew never returned.

The sub was found in waters off South Carolina in 1995 and raised five years later. It's been in the laboratory ever since.

Source: http://news.yahoo.com/experts-clues-sinking-confederate-sub-113855343.html

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Monday, January 28, 2013

Banner/Text Sales for Large Entertainment Website | Advertising ...

Tax Type Tax Rate Tax ID or Company no.

eg. VAT, GST ? Registration no.

Source: http://www.freelancer.com/projects/Internet-Marketing-Sales/Banner-Text-Sales-for-Large.html

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Computers and Technology|Hardware: Various Server Options For ...

Are you planning to setup an office which is complete in computer equipment, networking tools, and other IT infrastructure? If so, one of the many things you might be concerned with right now is how to pick the right server option that fits your newly established business. The truth is, there are many alternatives out there and it is easy to get lost with every tech solution presented by IT resellers and retailers.

However, if you want the best choice of server for your fledgling business, you need to be aware of the following options to select from:

Dedicated Server Options

Dedicated servers are hot because it provides computer administrators the capacity to have full control over their operations. This is the best option if you are running a business operation which requires your personnel to communicate and collaborate with their colleagues on multiple floors or locations. For example, instead of relying on an internet service provider to provide internet connections to your workstation computers, a dedicated server can provide its own connection in-house.

When it comes to uploading files into private archives, dedicated servers also works best for medium to large population staff because these types of servers are known for being able to handle huge amounts of traffic, storage data, or bandwidth. That means, if you run an intranet in your office or a shared virtual workspace, your dedicated server can handle it.

The only slight downside of dedicated servers is that you need to handle all the maintenance, software or hardware upgrades, and technical troubleshooting on your own.

Cloud Servers

These are servers which can be found "in the cloud", or in simpler language, servers that can be accessed, modified and configured online. This type of server is relatively new in the industry and it is revolutionary because it allows people and companies to send and store their data while using minimal hardware. Through a cloud server, a web administrator can easily control other servers within a virtual private network. File sharing and archiving is also made much easier through this amazing option.

Blade Servers

Blade servers function pretty much like any other high-end server, but the only difference is that it is optimized to conserve space and energy within your work environment. Because of its modular design, blade servers can easily fit in very small office space. This is ideal for companies who are just starting out to do business. These types of start-up business can still enjoy smooth employee communication and IT processes even with minimum space and budget.

One of the best ways to save money on your server and data storage device purchases is to get your IT equipment from an independent IT reseller. This way you can have a wide array of server options to choose from, as well as lower markup rates. Many companies save thousands of dollars per year by doing this.

Source: http://hardwarehelps.blogspot.com/2013/01/various-server-options-for-smooth.html

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Sunday, January 27, 2013

Truth, Money, Right, Wrong

Image (1) cnet.png for post 10277Yesterday I wrote about the ongoing CNET editorial independence issue. I said that the editors and journalists at CNET were part of the problem, and suggested that they either publish their (assumed) dissent, or resign, or both. A conversation began in the comments of that post, with some people saying that it isn’t reasonable to expect people to resign. From Danny Sullivan: I think a lot of CNET staffers probably aren’t resigning, Mike, because they have families to support, as well as themselves. It’s not exactly a great economy out there. I think what Greg did was very brave, but not everyone is that brave nor even able to make that type of move. Rof Hof: I don’t blame people in today’s publishing business for wanting to line up work first. Not everybody can be sure of being able to support their families, and when they’ve been screwed by their employer, they shouldn’t be expected to *immediately* screw themselves too. But don’t be surprised to see more leaving. There were similar comments on Twitter. These comments were often combined with statements my position wasn’t valid because I have made some money selling my business. As just one example, David Carnoy, Executive Editor at CNET, says: @arrington In your post about @CNET you neglected to disclose $$$ you made from selling out to AOL. Easy to walk when you had your BIG EXIT. And finally, some people have said that it’s only reasonable for people to resign if they have another job lined up. Hunter Walk, in a comment to the original post, says: Let’s see other journalists stand with their brethren and start a “free the CNET staffers” fund that can be tapped by any CNET journalist who wants to walk away but needs the money to do so. Mike, I’ll match up to the first $500 of your contribution I think some of these are valid points and worth exploring. First, sure it’s easy for me to say they should just quit their jobs when I’m not the one doing it and I may have more financial security than most or all of them. If I worked at CNET, had a family to take care of and had little financial breathing room I cannot say for certain that I’d resign. My family would certainly come first (and second, and third). It’s a fair point. Second, I agree that it

Source: http://feedproxy.google.com/~r/Techcrunch/~3/kUJJH10w3QY/

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Camco 36153 RV Brass Blow Out Plug Reviews

List price: $ 6.71

Camco 36153 RV Brass Blow Out Plug

  • Helps clear the water lines in your RV during winterization and dewinterization
  • Built with brass
  • Screws into RV city water inlet
  • Heavy duty
  • Easy to use

Completely clear your water lines with the Camco RV Brass Blow Out Plug. Screw the plug into the city water inlet, open all drains and faucets, attach and activate the air pump until all lines are clear. Patented.

Source: http://atixi.com/camco-36153-rv-brass-blow-out-plug-reviews/

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Republican Leaders Have Obama Campaign Envy

CHARLOTTE, N.C. ? For all the grumbling about President Obama at this week's gathering of Republican Party leaders, there's one thing they concede he's really good at: winning elections.

So many of them are eager to adopt strategies ripped from the Democratic campaign playbook: deploying campaign operatives in battleground states year-round; building "relationships" and "trust" in Hispanic and African-American neighborhoods; using social media to bring people together face to face; and most of all, a lot of "listening" to the grassroots. (Recipients of the Obama campaign?s earnest and frequent e-mails get it.)

?Community organizing? Sign me up!" said Florida Republican Party Chairman Lenny Curry, alluding to the president?s former occupation and the underlying spirit of his grassroots campaign. ?We?re going to find ways to engage with diverse communities.?

?It?s about finding out what the people in a precinct care about, because if you know that, then they are more likely to listen to you,? said North Carolina Republican Party Chairman Robin Hayes, echoing the Obama campaign?s success at compiling an unprecedented amount of information about individual voters in order to connect with them. ?

While there?s overwhelming consensus that the Republican National Committee needs to ramp up outreach to an increasingly diverse electorate and update its technology for voter contacts, Republicans remain divided on how deep their problems go. Can they make another run at Hispanic voters simply by changing their ?tone? or by upping their investment in Spanish-language media, or does the party need to offer new policy prescriptions, like immigration reform? The RNC?s Growth and Opportunity Project, which is collecting input from rank-and-file Republicans and offering recommendations for future campaigns, is not a policymaking body. More telling will be the upcoming battle on Capitol Hill over offering legal residency to the 11 million illegal immigrants in this country, which will undoubtedly shape the GOP?s ability to court minority voters in 2014 and 2016.

Even more complicated for Republicans will be positioning themselves on issues considered anathema to their conservative base, like abortion and gay marriage, but finding increasing acceptance in the mainstream and especially among women and young voters.

?We talked a lot more about messaging than policy,? said Oklahoma Republican Party Chairman Matt Pinnell. ?It?s outreach to all of the above. We don?t need to water down our policies or back away from our principles, but it?s the way we talk about those issues.?

Ari Fleischer, a White House spokesman under former President George W. Bush and one of five leaders of the Growth and Opportunity Project, put it this way: ?Republicans talk policy and Democrats talk people. Republicans can learn from Democrats how to make those connections."

What?s unclear is whether the strategies pioneered by a history-making president can be replicated at a time when the Republican Party is casting about for leadership. ?Is it House Speaker John Boehner? Our presidential candidates in 2016? Or a bunch of people on cable TV trying to raise their profile?? asked Mississippi-based campaign strategist Henry Barbour, another Growth and Opportunity Project cochair. Then-Senate candidate Obama rose to national prominence in his speech at the 2004 Democratic convention, when he dismissed the idea of ?red? states and ?blue? states and declared ?there?s the United States of America.? He went on to remake the 2008 campaign map in his presidential run by sweeping states that hadn?t voted Democrat in decades.

?Being a blue state is not a permanent diagnosis,? said Republican National Committee Chairman Reince Priebus on Friday, taking Obama's cue. ?We must be a party concerned about every American in every neighborhood.?

Priebus also vowed to develop a ?permanent, national field infrastructure,? an operation that could cost the party millions of additional dollars. Colorado Republican Party Chairman Ryan Call said that already he is raising money to put ?regional campaign organizers? on the ground year-round, four by March and eight to 10 by the end of the year. ?We?re not waiting for the RNC to do it,? he said. ?We need to be engaging with voters all of the time, not just five months before the election.?

Sounds familiar. Shortly after the 2008 election, Obama?s team launched a permanent campaign apparatus called Organizing for America to nurture and grow the grassroots network built during the campaign. The group had limited success promoting the administration?s agenda but undoubtedly laid the early groundwork for his reelection bid. Now the organization is retooling as a tax-exempt organization outside the Democratic National Committee.

?As a party, we must recognize that we live in an era of permanent politics,? Priebus said. ?We must stop living nominee-to-nominee, campaign-to-campaign. As we saw this election, our opponent benefited from a multiyear head start.?

Priebus was overwhelmingly reelected to a second term at an uneventful meeting Friday that contrasted with the fireworks two years ago when financial problems sunk former Chairman Michael Steele?s reelection bid, despite Republican gains in the 2010 election. Priebus is widely praised for paying off the $24 million debt he inherited.

?Ordinarily you?d think we?d be throwing folks overboard, but instead we are taking a step back,? said Massachusetts GOP National Committeeman Ron Kaufman, who added that the national party and Mitt Romney's campaign together raised $1 billion. ?People credit Reince Priebus for bringing us back from the abyss.?

Kaufman was a top Romney adviser who admitted to still feeling ?depressed, actually it?s more of a funk.? What has uplifted many GOP activists after Romney?s resounding loss are their leaders back home. That 30 of the nation?s governors are Republicans was repeatedly mentioned during this week?s party gathering. So was the promise of the potential Republican field in 2016, a younger and more diverse crowd exemplified by the 41-year-old Indian-American governor of Louisiana, Bobby Jindal, who addressed the activists Thursday night.

On the Democratic side, most of the possible 2016 contenders are white men, with the notable exception of Secretary of State Hillary Rodham Clinton.

Meantime, the RNC is reviewing 24,000 responses to its online survey, talking to hundreds of activists and political pros, and scheduling "listening sessions" from Miami to Seattle. The effort is reminiscent of the Obama team's efforts to help volunteers feel invested. "It's not copying Obama," Kaufman said. "It's catching up."

Source: http://news.yahoo.com/republican-leaders-obama-campaign-envy-163140156--politics.html

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Saturday, January 26, 2013

Katy Perry's Face on Paula Deen: Because the Internet Can

Source: http://www.thehollywoodgossip.com/2013/01/katy-perrys-face-on-paula-deen-because-the-internet-can/

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Facebook won't let Twitter's Vine find friends

22 hrs.

Twitter's Vine officially launched on Thursday and things have already been fairly rough for the?new video-sharing service. First we noticed that it seems to lack any proper privacy settings or features and now it seems as if Facebook's preventing Vine from finding any friends.

As the Verge's Jeff Blagdon points out, some Twitter users are calling attention to an error message which appears when they attempt to find Facebook friends on Vine. "Vine is not authorized to make this Facebook request," the message explains.

We reached out to both Facebook and Twitter to find out more about this error message. A Twitter spokesperson responded with a polite message pointing us to a post on the official Facebook developers blog. (Yes, yes. This made us chuckle for a moment, too.)

In the blog post, Facebook's Justin Osofsky, director of platform partnerships and operations, clarifies some of the social network's platform policies.?He basically explains that most apps use Facebook's platform to give people an easy way to log into apps, easily share content and so on. But, he writes, there is a small number of apps which are "using Facebook to either replicate [its] functionality or bootstrap their growth in a way that creates little value for people on Facebook."

"[W]e?ve had policies against this that we are further clarifying today," he writes, linking to the social network's platform policies page, which explains why Vine's cut off:

Facebook Platform enables developers to build personalized, social experiences via the Graph API and related APIs. If you use any Facebook APIs to build personalized or social experiences, you must also enable people to easily share their experiences back with people on Facebook. [...]?You may not use Facebook Platform to promote, or to export user data to, a product or service that replicates a core Facebook product or service without our permission.

In other words: No, Vine. You can't make friends by leaning on Facebook.

Of course, this siliness?is just the latest skirmish in a long battle over "friends" between Facebook and Twitter.?Facebook blocked Twitter's access to the social network's in-app friend finder in mid-2010 and Twitter later killed Instagram's ability to find friends easily. (Instagram, as you may remember, is now owned by Facebook.

Guess it's Twitter's turn to do something again.

Want more tech news?or interesting?links? You'll get plenty of both if you keep up with Rosa Golijan, the writer of this post, by following her on?Twitter, subscribing to her?Facebook?posts,?or circling her?on?Google+.

Source: http://www.nbcnews.com/technology/technolog/facebook-preventing-twitters-vine-finding-friends-1C8119018

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P53 mutation hinders cancer treatment response

Jan. 25, 2013 ? Scientists from the National Cancer Centre Singapore (NCCS) have discovered the workings of the gene that has been hindering treatment response in cancer patients. This discovery was made after 5 years of studying the mutant form of the p53 gene, the major tumor suppressor in humans, which is generally found mutated in over 50% of all type of human cancers.

The dominant-negative (DN) effect of the mutant p53 gene in cancers was found to affect the outcome of cancer treatment modalities. DN effect is a phenomenon whereby one copy of mutant p53 that exists in cancer cells inhibits the tumor suppressor activity of the other wild-type p53 copy when they co-exist. The result is that a patient may either have poor response or earlier relapse of tumours after their treatment.

The research findings is significant in that it offers hope to improve cancer treatment outcomes by selectively inhibiting mutant p53's DN effect through several methods by generating selective and specific inhibitory molecules specific for some of the common hot-spot p53 point mutations. There are currently no drugs or compounds that can alleviate DN effects of mutant p53.

In order to understand the specific roles of mutant p53 DN properties in regulating acute treatment response and long-term tumourgenesis, a team of five researchers led by NCCS Prof Kanaga Sabapathy, the Principal Investigator in the Laboratory of Carcinogenesis and Head of the Division of Cellular & Molecular Research from NCCS, carried out experiments by generating genetically engineered knock-in mouse strains expressing varying levels of mutant p53. The results showed that DN effect is observed after acute p53 activation by a variety of chemotherapeutic drugs and irradiation, thereby affecting anti-cancer treatment. This breakthrough came after five years of intensive research.

It was found that mutant p53 have DN effects in a cell-type and dose-dependent manner, especially during acute p53 activation where p53 levels are elevated. Based on the above observations, efforts to generate specific inhibitors for the common hot spot p53 point mutations are underway. The inhibition of mutant p53 expression in cells carrying a wild-type and mutant p53 alleles can improve response to chemotherapeutic drugs.

In a further study, the researchers also questioned the possibility of the mutant p53 acquiring new functions (or Gain of Function) to drive carcinogenesis, transforming normal cells to cancerous cells. Their investigation comparing cells from genetically engineered mouse strains expressing 2 different types of p53 mutations: the R172H mutation versus the R246S mutation, which showed that Gain of Function (GOF) was found only in the former. This showed that GOF of mutated p53 is specifically dependent on mutation-type but not across all kinds of genetic mutations, highlighting diversity in properties of the different types of p53 mutations, thereby indicating that mutations found in human cancers can behave differently, and thus, need to be carefully assessed prior to treatment.

Thus, the existence of mutant p53 certainly has a negative impact on cancer treatment, whether it is through DN effect or GOF. Prof Sabapathy said that the team is now embarking on more research to determine the possibility of targeting mutant p53 without affecting wild-type p53 in human cells, paving way to clinical trials in the future to test the efficacy on cancer therapeutic response.

The research was supported by grants from the National Medical Research Council of Singapore and the Singapore Millennium Foundation to KS. The publication has been accepted and published by Cell Press, publisher of biomedical journals, in the journal Cancer Cell, on Dec. 10, 2012. Prof Sabapathy also teaches at the Duke-NUS Graduate Medical School.

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Story Source:

The above story is reprinted from materials provided by SingHealth, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Ming?Kei Lee, Wei?Wei Teoh, Beng?Hooi Phang, Wei?Min Tong, Zhao?Qi Wang, Kanaga Sabapathy. Cell-type, Dose, and Mutation-type Specificity Dictate Mutant p53 Functions In?Vivo. Cancer Cell, 2012; 22 (6): 751 DOI: 10.1016/j.ccr.2012.10.022

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/EAuE68IgufU/130125111331.htm

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Friday, January 25, 2013

Arrest made in young Philly doctor's killing

PHILADELPHIA (AP) ? An arrest has been made in the slaying of a young doctor found bound and burned inside her downtown Philadelphia home.

Police spokeswoman Officer Tanya Little said Thursday morning that a person is in custody. Authorities did not immediately release details on the charges being filed or the person's name.

The burning body of 35-year-old Melissa Ketunuti was found in her basement Monday afternoon, with her ankles and wrists bound. Police said the second-year infectious-diseases fellow and researcher at Children's Hospital of Philadelphia had been strangled.

The police department says it will be releasing updated information on the case Thursday.

Investigators had been viewing surveillance video from security cameras near Ketunuti's home to see if she was being followed.

Source: http://news.yahoo.com/arrest-made-young-philly-doctors-killing-142353534.html

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Audi's "Choose Your Own Adventure" Super Bowl Ads

?

The internet has effectively ruined the suspense of waiting to see high profile Super Bowl commercials, but Audi attacks the crucial pre-game timeframe this year using a different tack.

?

The setup: A high schooler is iffy about attending prom on his own until his dad lends him the keys to the family S6. After a spirited drive to school (which includes parking in the principal's spot), the newly emboldened kid kisses the prom queen. Three subsequent outcomes will be voted on by the YouTube Nation over a 24 hour period, and the winning selection will air during the big game.

?

We're not sure the concept is pulled off with enough ?lan to warrant the hoopla Audi has earned in years past, especially with clever spots like this?occupying a solid spot in the pantheon of the greatest Super Bowl car commercials of all time. But if you don't mind feeding Audi's obligatory pre-Superbowl hype machine, you can view the proto-ads on Audi's official YouTube channel?before the winner is announced on January 26.

Source: http://www.popularmechanics.com/cars/news/auto-blog/audi-super-bowl-ad-concept-choose-your-own-adventure?src=rss

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Millionaire Man: 5 Ways to Improve Your Business Security and ...

Millionaire Man: 5 Ways to Improve Your Business Security and Make Millions! skip to main | skip to sidebar

5 Ways to Improve Your Business Security and Make Millions!

The Internet has become a fundamental tool for many businesses across the world. There are now over 2,400 million people with access to the World Wide Web, making it an irreplaceable marketing and communication tool.??As?the world advances technically,?the chance of hackers gaining unauthorized access to your sensitive data?does increase. It is essential to protect your business and your customer base with products,?for example an?X509 Digital Certificate?or the trusted?VeriSign?stamp, to ensure security and confidence while using your online platforms.?1.????? Invest in?an?X509 Digital Certificate?Online hardware no longer starts and ends with the desktop computer or your laptop. Mobile devices are now able to connect to?your servers and access data at?the tap of an app. An X509 Digital Certificate can be purchased by manufacturers, and embedded into hardware to ensure that only authorized access is granted to named devices.?2.????? Add a?SSL?Certificate to your Website?Encrypt any information passed through your website with a?SSL?Certificate. Show customers and/or clients that your website is trustworthy and can be used without worry.?Get the VeriSign seal of approval.?3.????? Look into Extended Verification for Ecommerce Businesses?SSL?EV?is extended verification and offers additional encryption services for businesses who provide ecommerce facilities on their website. Take customer card details in confidence, while buyers will browse safe in the knowledge that they are purchasing goods or services from a trusted retailer. Gain the green address bar, the padlock stamp and the https:// status.?4.????? Encrypt your Emails?Invest in a Wildcard?SSL?Certificate and extend your?SSL?Certificate to cover multiple sub domains on your website, as well as email encryption.?5.????? Follow Basic Data Protection Pathways?Sometimes it is all too?easy to get stuck into the technicalities of business. Ensure that basic data protection pathways are followed ? lock away any confidential paperwork and log out of computers following active sessions.?

?

Source: http://millionairedad.blogspot.com/2013/01/5-ways-to-improve-your-business.html

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